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Pharmacogenetics DNA test of urological pathologies
Pharmacogenetics DNA test of urological pathologies
DNA test that studies the genetic polymorphisms, related to the therapeutic efficacy of the treatment of urological pathologies, in order to select the most appropriate drugs and the most appropriate dose for each person.
Precio: 
425 €

Sample type:

Saliva

Delivery period:

30 - 40 days from sample receipt.
Last update of the document Sep, 29/09/2021 - 10:53

Pharmacogenetics DNA test of urological pathologies

Profile of Pharmacogenetics that studies the genetic polymorphisms related to the therapeutic efficacy of drugs for erectile dysfunction, premature ejaculation, prostate hyperplasia, overactive bladder and aromatase inhibitors in order to select the most appropriate and dose, in a personalized way .

Pharmacogenetics studies the actions and interactions between individual drugs for each person based on their genes. A genetic change can modify both the pharmacokinetics and the pharmacodynamics, which can produce toxicity or therapeutic failure in the treatment.

Pharmacogenetics currently applied in clinical practice is mainly based on the metabolism of drugs via the liver. They emphasize the cytochromes P450, or CYPs. The CYPs influence many enzymes involved in the metabolism of various substances both external (e.g. environmental pollutants or drugs) and endogenous (e.g. hormones). The genes involved in the response to drugs that exhibit variability, such as some transporters, phase II enzymes and pharmacological targets whose effect is contrasted, are relevant

Most of these enzymes present differences between people. So we know that there are variants with more activity, less activity or non-functional. This conditions the speed of metabolism and elimination of drugs. Some active ingredients have no biological activity in the way and are administered through metabolism active molecule is generated; they are the prodrugs. Variations in the ability of metabolism of prodrugs, can prevent the formation of active drug.

This test analyzes the main CYP enzymes responsible for the metabolism of drugs, covering the polymorphisms with frequency higher than 1%, so that it has an excellent coverage of the genetic variability in drug metabolism.

Interpretation of the report in Polytherapy

In this report, the "green" labeling of a certain drug with the patient's genes indicates that it can be prescribed in the standard dose conditions disclosed in the prospectus or those recommended by the physician. This applies in the case of monotherapy.

However, if the patient takes several medications, which is very common, although in the report would appear in "green" can cause adverse effects due to possible interactions between them, which can sometimes be severe, either by toxicity or by therapeutic failure.

Drugs are chemicals that may interfere the normal metabolism of other drugs. Interferences that are also applicable to the chemical substances of various medicinal plants and food supplements.

Consequently, the whole of the medication, together with the consumer products or life habits of the patient, must undergo an evaluation of pharmacological interactions.

Consulting g-Nomic® Pharmacogenetics interpretation software, before prescribing, is an effective aid to avoid most adverse effects or therapeutic failures due to medication.

g-Nomic® interrelates all drugs, herbs, nutritional supplements and lifestyle, with the patient's genes. It also advises the most appropriate dose to prescribe.

This text has been translated automatically using an electronic translator, so the Spanish version should prevail. Please check in case of doubt.

You will receive the sample collection kit. You can request additional kits if you need it.

Sample collection kit content:
You will get a box with sample collection kit. Within the kit you will find:

  1. Saliva collector.
  2. Instructions for the sample collection.
  3. Informed consent sheet and application form.
  4. Security bag to enter the sample for shipment.
  5. Envelope bag.

Process to follow:

  1. Follow the instructions for collecting the sample.
  2. After obtaining the sample, include it in the return envelope, remember to put into the informed consent sheet and the application form.
  3. No shipping costs on Spanish territory.
  4. An email confirmation will be sent when your sample si received.
  5. When the study will be completed you will receive a new e-mail to inform you that your report is already available in "My results".

Info producto mobile

Profile Information

Pharmacogenetics DNA test of urological pathologies

Profile of Pharmacogenetics that studies the genetic polymorphisms related to the therapeutic efficacy of drugs for erectile dysfunction, premature ejaculation, prostate hyperplasia, overactive bladder and aromatase inhibitors in order to select the most appropriate and dose, in a personalized way .

Pharmacogenetics studies the actions and interactions between individual drugs for each person based on their genes. A genetic change can modify both the pharmacokinetics and the pharmacodynamics, which can produce toxicity or therapeutic failure in the treatment.

Pharmacogenetics currently applied in clinical practice is mainly based on the metabolism of drugs via the liver. They emphasize the cytochromes P450, or CYPs. The CYPs influence many enzymes involved in the metabolism of various substances both external (e.g. environmental pollutants or drugs) and endogenous (e.g. hormones). The genes involved in the response to drugs that exhibit variability, such as some transporters, phase II enzymes and pharmacological targets whose effect is contrasted, are relevant

Most of these enzymes present differences between people. So we know that there are variants with more activity, less activity or non-functional. This conditions the speed of metabolism and elimination of drugs. Some active ingredients have no biological activity in the way and are administered through metabolism active molecule is generated; they are the prodrugs. Variations in the ability of metabolism of prodrugs, can prevent the formation of active drug.

This test analyzes the main CYP enzymes responsible for the metabolism of drugs, covering the polymorphisms with frequency higher than 1%, so that it has an excellent coverage of the genetic variability in drug metabolism.

Interpretation of the report in Polytherapy

In this report, the "green" labeling of a certain drug with the patient's genes indicates that it can be prescribed in the standard dose conditions disclosed in the prospectus or those recommended by the physician. This applies in the case of monotherapy.

However, if the patient takes several medications, which is very common, although in the report would appear in "green" can cause adverse effects due to possible interactions between them, which can sometimes be severe, either by toxicity or by therapeutic failure.

Drugs are chemicals that may interfere the normal metabolism of other drugs. Interferences that are also applicable to the chemical substances of various medicinal plants and food supplements.

Consequently, the whole of the medication, together with the consumer products or life habits of the patient, must undergo an evaluation of pharmacological interactions.

Consulting g-Nomic® Pharmacogenetics interpretation software, before prescribing, is an effective aid to avoid most adverse effects or therapeutic failures due to medication.

g-Nomic® interrelates all drugs, herbs, nutritional supplements and lifestyle, with the patient's genes. It also advises the most appropriate dose to prescribe.

This text has been translated automatically using an electronic translator, so the Spanish version should prevail. Please check in case of doubt.

Sample type and process to follow

You will receive the sample collection kit. You can request additional kits if you need it.

Sample collection kit content:
You will get a box with sample collection kit. Within the kit you will find:

  1. Saliva collector.
  2. Instructions for the sample collection.
  3. Informed consent sheet and application form.
  4. Security bag to enter the sample for shipment.
  5. Envelope bag.

Process to follow:

  1. Follow the instructions for collecting the sample.
  2. After obtaining the sample, include it in the return envelope, remember to put into the informed consent sheet and the application form.
  3. No shipping costs on Spanish territory.
  4. An email confirmation will be sent when your sample si received.
  5. When the study will be completed you will receive a new e-mail to inform you that your report is already available in "My results".

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