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LACTOgenes

DNA test of lactose intolerance
DNA test of lactose intolerance
Lactose intolerance DNA testing, a condition of the intestinal mucosa resulting from the little or no lactase enzyme production, which results in a failure to metabolize lactose
Precio: 
99 €

Sample type:

Saliva

Delivery period:

16 days from sample receipt
Last update of the document May, 17/05/2023 - 14:13

Lactose intolerance DNA test

Lactose intolerance should not be confused with lactose allergy.

Lactose intolerance is characterized by a total or partial absence of lactase enzyme responsible for digesting lactose, in dairy products such as milk, butter, yogurt or cheese sugar.

Undigested lactose passes the small intestine to the colon where it is fermented by enteric bacteria, producing copious amounts of gas. This may cause symptoms of colic, nausea, diarrhea, flatulence, as well as headaches, which usually appear between 30 minutes and 2 hours after the ingestion of dairy products.

Lactase is an enzyme encoded by a gene of chromosome 2 that all mammals have, this allows them to tolerate milk during the lactation period. As this stage is left behind, the expression of the gene decreases and therefore the synthesis of lactase, so that the intestine loses the ability to assimilate lactose, that is, the sugar in milk.

However, the human species, unlike the rest of mammals, developed a polymorphism of the LACT gene between 5,000 and 7,000 years ago, coinciding with the sedentary life habits of the Neolithic. Thanks to this "adaptive" mutation, synthesis activity of lactase remains in certain persons and their descendants, which continue tolerating lactose after weaning.

This mutation is highly dependent on the race. For example, in Sweden, there is only 2% intolerant. In USA 12% of Caucasians are intolerant. Among Native American Indians, almost 100% are intolerant. In Latin America 50% of the population is lactose intolerant and in the south of Europe it can approach 50%. In Spain it affects between 15% and 20% of the population.

To know if a patient is tolerant or not to lactose, the LACTOgenes profile analyzes whether the LACT gene presents the polymorphism that maintains lactose tolerance, or the person presents or will present intolerance.

You will receive the sample collection kit. You can request additional kits if you need it.

Sample collection kit content:
You will get a box with sample collection kit. Within the kit you will find:

  1. Saliva collector.
  2. Instructions for the sample collection.
  3. Required documents
  4. Security bag to enter the sample for shipment.
  5. Envelope bag.

Process to follow:

  1. Fill in the documents that we will send you, duly signed. You can also find these documents on this page, under the web tab: "Documents required".
  2. Follow the instructions for collecting the sample.
  3. After obtaining the sample, include it in the return envelope remember to put into the necessary documents.
  4. Call Eugenomic® on +34 93 292 29 63 or email info@eugenomic.com to request sample collection. No shipping costs on Spanish territory.
  5. An email confirmation will be sent when your sample si received.
  6. When the study will be completed you will receive a new e-mail to inform you that your report is already available in "My results"

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Profile Information

Lactose intolerance DNA test

Lactose intolerance should not be confused with lactose allergy.

Lactose intolerance is characterized by a total or partial absence of lactase enzyme responsible for digesting lactose, in dairy products such as milk, butter, yogurt or cheese sugar.

Undigested lactose passes the small intestine to the colon where it is fermented by enteric bacteria, producing copious amounts of gas. This may cause symptoms of colic, nausea, diarrhea, flatulence, as well as headaches, which usually appear between 30 minutes and 2 hours after the ingestion of dairy products.

Lactase is an enzyme encoded by a gene of chromosome 2 that all mammals have, this allows them to tolerate milk during the lactation period. As this stage is left behind, the expression of the gene decreases and therefore the synthesis of lactase, so that the intestine loses the ability to assimilate lactose, that is, the sugar in milk.

However, the human species, unlike the rest of mammals, developed a polymorphism of the LACT gene between 5,000 and 7,000 years ago, coinciding with the sedentary life habits of the Neolithic. Thanks to this "adaptive" mutation, synthesis activity of lactase remains in certain persons and their descendants, which continue tolerating lactose after weaning.

This mutation is highly dependent on the race. For example, in Sweden, there is only 2% intolerant. In USA 12% of Caucasians are intolerant. Among Native American Indians, almost 100% are intolerant. In Latin America 50% of the population is lactose intolerant and in the south of Europe it can approach 50%. In Spain it affects between 15% and 20% of the population.

To know if a patient is tolerant or not to lactose, the LACTOgenes profile analyzes whether the LACT gene presents the polymorphism that maintains lactose tolerance, or the person presents or will present intolerance.

Sample type and process to follow

You will receive the sample collection kit. You can request additional kits if you need it.

Sample collection kit content:
You will get a box with sample collection kit. Within the kit you will find:

  1. Saliva collector.
  2. Instructions for the sample collection.
  3. Required documents
  4. Security bag to enter the sample for shipment.
  5. Envelope bag.

Process to follow:

  1. Fill in the documents that we will send you, duly signed. You can also find these documents on this page, under the web tab: "Documents required".
  2. Follow the instructions for collecting the sample.
  3. After obtaining the sample, include it in the return envelope remember to put into the necessary documents.
  4. Call Eugenomic® on +34 93 292 29 63 or email info@eugenomic.com to request sample collection. No shipping costs on Spanish territory.
  5. An email confirmation will be sent when your sample si received.
  6. When the study will be completed you will receive a new e-mail to inform you that your report is already available in "My results"

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