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Anticoagulants DNA test
Hypercoagulable states may occur by inherited (genetic) factors, or acquired, such as atherosclerosis, postoperative or prolonged immobilization.
Anticoagulants and antiplatelet drugs have a narrow therapeutic index. They must be carefully selected and dosed.
The therapeutic effect is at a delicate balance point between poor anticoagulation, which could lead to a thrombotic event, and excessive anticoagulation, for example, due to a reduced metabolism, which increases the risk of bleeding.
There are several drugs used to prevent thrombosis, which can be classified into anticoagulants, which act on the coagulation cascade, and antiplatelet drugs, which reduce platelet adhesion.
Several genetic factors influence the activation and elimination of these drugs.
The most common family is coumarin anticoagulants that act to neutralize vitamin K. The best known drug is warfarin, (acenocoumarol in Spain), pharmacokinetic profile, pharmacodynamic and pharmacogenetic equivalent.
Non-coumarin anticoagulants are irreversible inhibitors of coagulation. Genetic factors may contribute to have more risk of adverse effects. Its effect cannot be routinely monitored and there is no antidote in case of trauma.
Platelet antiaggregants are used for the prevention of arterial thromboembolism. The most commonly used are acetylsalicylic acid and clopidogrel.
Platelet anticoagulants and antiplatelet drugs have numerous interactions with other medications and with lifestyles, both pharmacokinetically and pharmacodynamically. These drugs have fewer documented interactions, but they should not be overlooked, as they have a narrow therapeutic index.
The ANTICOAGULANTSpgx profile studies the main categories and drugs related to anticoagulant treatment. The report includes an interpretation of the results for the 9 most frequent prescription drugs.
Interpretation of the report in Polytherapy
In this report, the "green" labeling of a certain drug with the patient's genes indicates that it can be prescribed in the standard dose conditions disclosed in the prospectus or those recommended by the physician. This applies in the case of monotherapy.
However, if the patient takes several medications, which is very common, although in the report would appear in "green" can cause adverse effects due to possible interactions between them, which can sometimes be severe, either by toxicity or by therapeutic failure.
Drugs are chemicals that may interfere the normal metabolism of other drugs. Interferences that are also applicable to the chemical substances of various medicinal plants and food supplements.
Consequently, the whole of the medication, together with the consumer products or life habits of the patient, must undergo an evaluation of pharmacological interactions.
Consulting g-Nomic® Pharmacogenetics interpretation software, before prescribing, is an effective aid to avoid most adverse effects or therapeutic failures due to medication.
g-Nomic® interrelates all drugs, herbs, nutritional supplements and lifestyle, with the patient's genes. It also advises the most appropriate dose to prescribe.
This text has been translated automatically using an electronic translator, so the Spanish version should prevail. Please check in case of doubt.
You will receive the sample collection kit. You can request additional kits if you need it.
Sample collection kit content:
You will get a box with sample collection kit. Within the kit you will find:
- Saliva collector.
- Instructions for the sample collection.
- Required documents
- Security bag to enter the sample for shipment.
- Envelope bag.
Process to follow:
- Fill in the documents that we will send you, duly signed. You can also find these documents on this page, under the web tab: "Documents required".
- Follow the instructions for collecting the sample.
- After obtaining the sample, include it in the return envelope remember to put into the necessary documents.
- Call Eugenomic® on +34 93 292 29 63 or email info@eugenomic.com to request sample collection. No shipping costs on Spanish territory.
- An email confirmation will be sent when your sample si received.
- When the study will be completed you will receive a new e-mail to inform you that your report is already available in "My results"
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Anticoagulants DNA test
Hypercoagulable states may occur by inherited (genetic) factors, or acquired, such as atherosclerosis, postoperative or prolonged immobilization.
Anticoagulants and antiplatelet drugs have a narrow therapeutic index. They must be carefully selected and dosed.
The therapeutic effect is at a delicate balance point between poor anticoagulation, which could lead to a thrombotic event, and excessive anticoagulation, for example, due to a reduced metabolism, which increases the risk of bleeding.
There are several drugs used to prevent thrombosis, which can be classified into anticoagulants, which act on the coagulation cascade, and antiplatelet drugs, which reduce platelet adhesion.
Several genetic factors influence the activation and elimination of these drugs.
The most common family is coumarin anticoagulants that act to neutralize vitamin K. The best known drug is warfarin, (acenocoumarol in Spain), pharmacokinetic profile, pharmacodynamic and pharmacogenetic equivalent.
Non-coumarin anticoagulants are irreversible inhibitors of coagulation. Genetic factors may contribute to have more risk of adverse effects. Its effect cannot be routinely monitored and there is no antidote in case of trauma.
Platelet antiaggregants are used for the prevention of arterial thromboembolism. The most commonly used are acetylsalicylic acid and clopidogrel.
Platelet anticoagulants and antiplatelet drugs have numerous interactions with other medications and with lifestyles, both pharmacokinetically and pharmacodynamically. These drugs have fewer documented interactions, but they should not be overlooked, as they have a narrow therapeutic index.
The ANTICOAGULANTSpgx profile studies the main categories and drugs related to anticoagulant treatment. The report includes an interpretation of the results for the 9 most frequent prescription drugs.
Interpretation of the report in Polytherapy
In this report, the "green" labeling of a certain drug with the patient's genes indicates that it can be prescribed in the standard dose conditions disclosed in the prospectus or those recommended by the physician. This applies in the case of monotherapy.
However, if the patient takes several medications, which is very common, although in the report would appear in "green" can cause adverse effects due to possible interactions between them, which can sometimes be severe, either by toxicity or by therapeutic failure.
Drugs are chemicals that may interfere the normal metabolism of other drugs. Interferences that are also applicable to the chemical substances of various medicinal plants and food supplements.
Consequently, the whole of the medication, together with the consumer products or life habits of the patient, must undergo an evaluation of pharmacological interactions.
Consulting g-Nomic® Pharmacogenetics interpretation software, before prescribing, is an effective aid to avoid most adverse effects or therapeutic failures due to medication.
g-Nomic® interrelates all drugs, herbs, nutritional supplements and lifestyle, with the patient's genes. It also advises the most appropriate dose to prescribe.
This text has been translated automatically using an electronic translator, so the Spanish version should prevail. Please check in case of doubt.
Sample type and process to follow
You will receive the sample collection kit. You can request additional kits if you need it.
Sample collection kit content:
You will get a box with sample collection kit. Within the kit you will find:
- Saliva collector.
- Instructions for the sample collection.
- Required documents
- Security bag to enter the sample for shipment.
- Envelope bag.
Process to follow:
- Fill in the documents that we will send you, duly signed. You can also find these documents on this page, under the web tab: "Documents required".
- Follow the instructions for collecting the sample.
- After obtaining the sample, include it in the return envelope remember to put into the necessary documents.
- Call Eugenomic® on +34 93 292 29 63 or email info@eugenomic.com to request sample collection. No shipping costs on Spanish territory.
- An email confirmation will be sent when your sample si received.
- When the study will be completed you will receive a new e-mail to inform you that your report is already available in "My results"